Home Forums Hunting & Shooting Hunting Rifles 6.5x55 for Moose? Really?

Can a moose tell the difference between a 0.568 inch hole (2x 0.264) and a 0.678 inch hole (2x 0.338) through its lungs/heart?

Assuming similar construction with 2x expansion of the bullet with similar penetration. Lets compare 160g Woodleigh in 6.5x55 and a 300g Woodleighs in .338. SD for the 6.5 is 0.328, SD for .338 is 0.375.