My Alaskan reeeeelly likes H4350, which I use most of the time. Still have about 10 lbs left.

260 gr AB in front of 85.5 gr.

However, will be trying some RL17 later.

Suggest you also go to "gunblast.com",,,,Click onto "archives"

Then, speed scroll down to 2/6/07 and see Jeff Quinn`s 375 Ruger African article. There, you`ll see about 20 loadings with chrony results.

Hodgdon also has, if I remember, 260 gr Nosler loadings on their site for the 375 Ruger.

His favorite powder for the 375 Ruger is H-4350


28 Nosler,,,,300WSM,,,,338-378 Wby,,,,375 Ruger