As I've stated many times, I'm not much of a hunter. I'm more interested in the technical aspects of the hobby. So real life experience trumps any of the following opinions:
There is reason to believe that a larger, heavier bullet will do a better job of surviving impact on a major bone and continuing with enough momentum or energy to complete its mission.
If the bullet does not have to penetrate a major bone, then the 6.5 and 308 bullets are probably quite similar in performance. If they do have to penetrate a large bone, then a heavier 308 bullet probably has an advantage.
