Hunting Alaska is more about "where" you'll hunt, and "how" you'll get there than about what you'll kill it with. Big country, and it can be very difficult to get to "where" the game is. A Moose is the easiest big game animal I've killed. All sorts of calibers will do the trick. Getting them out is the hard part.
I definately wouldn't want to do one solo. In fact, I don't want to be part of anymore Moose hunts if I can help it!
I'd be thinking more along the lines of quads, boats and planes than calibers.
Don't want to discourage you, but hunting in Alaska can often be more of an expedition than a hunt. At least compared to hunting the lower 48. Go for it, just get your bases covered before you head out.
