I hunt with a .270 Win, and I love it, it's a great, smooth firing gun. However, the 25-06 is also a good caliber. It's good for deer and also some smaller game, and even some bigger game. They are both great deer guns, and like everybody says, a 25-06 is a .270 that missed a week of workout, and it'll save your shoulder a bit. I know this really doesn't help you a whole lot, but this is my view on both guns.