The std 280 will shoot the 160g Nosler at 2900 fps...if you plan to reload...load of IMR 7828 right out of the Nosler manual.
That being said, the 7 Mag with a load of Retumbo will accuately shoot the 162's at 3100 fps.
I did the 280 AI thing, and ended up shooting about 3g less powder than the 7 mags with the 140's. Since my Rem 700's shoot tiny groups with the 140's, I sold the custom AI to a good friend.
The little 7/08 with 130g Speers and IMR 4895 is hell on wheels with white tails at 2850 fps...about 325 is as far as I have killed deer with this load and they were DRT.
What ever caliber you shoot, practice, know your trajectory, and place your shot, then all the calibers are all good. Never expect a magnum or a magic bullet type to make up for bad shot placement.
