It's "fun" to read that penetration is all we need from caliber and bullet smile. Take full metal jacket and allways have "good" penetration smile.
From my own experience in Africa:
Oryx from 300m lungs shot fell down but arise again and went 400m before was finally down...
Blue wildebeest from 150m shot went 5 inch behind front leg and slightly up...it "cost" 3 hours to find it and 2 extra shots to put it down
Both cases caliber was 9,3x64 what is equal to 375...
Therefore if you play with your own money, and that you do in Africa, take proper gun and proper ammo smile Do not play game what is the minimum caliber what take animal down...it might cost you lot of money smile