I've run the 180 ABs thru my 308 with Varget, R15, and IMR4064 in the 44-45 gr range. Also stoked 49 gr H414/W760 behind it with good results. As always work up if you give these a try. I've also had an itch to try R17 and Ramshot Big Game. My 308 is in a commercial 98 so I can seat the bullets out around 2.9" OAL and as such I get a little relief from compressed loads.