Breaking in my new Shiloh 45/110 and increasing the charge from 96 to 105grs of KIK 2F behind a 530gr Postel greaser was an eye opener of raw power these old cartridges were capable of.Not overpowering but yet I think you'd whip a good ole fashion azz whuppin on yourself if you bench shot 30-40 rds or would feel like you went 10 rounds with Joe Frazier!