I would first go with RE-19 and then 4350, the 19 up to 76 grs. in WW cases, mag.primers, I prefer CCI 250s and WWs, and cut a half grain from my CCI loads when using WW mag. primers.

I KNOW you CAN load a "tad" hotter, but, 74-76-RE-19 works VERY well in every .338WM I have seen it used in and I have come to prefer RE-19 and RE-22 over ANY powder in this, my favourite cartridge for 45+ years and 13 different rifles, have six pretty fine ones now.