As long as you keep the range to under 300 yards you should be fine. My first Elk, November of 1980, was harvested with a 30-06. It was all I had so I made it work. Enjoy your hunt and hunt with confidence.
I have seen large bull elk put down with the the OP's combo other than it was 4350 and 168 TSX at 450 yards. Not saying I advocate that distance, but it worked great.
