The 05 and 06 models have a 5 speed transmission that has proven to be very reliable. The 4.7 liter V8 (2UZ-FE) is one of the best gasoline engines ever made IMO. It's a proven drivetrain and if maintained properly should go over 300,000 miles.
Just remember that it's an interference engine and the timing belt has got to be changed every 90,000 miles. They are easy on oil and wear very well based on hundreds of UOA's over on BITOG
