Home Forums Hunting & Shooting Hunter's Campfire Maybe a real vaccine

A vaccine authorized in December for use in India may help solve one of the most vexing problems in global public health: How to supply lower-income countries with a COVID-19 vaccine that is safe, effective and affordable.

The vaccine is called CORBEVAX. It uses old but proven vaccine technology and can be manufactured far more easily than most, if not all, of the COVID-19 vaccines in use today.

"CORBEVAX is a game changer," says Dr. Keith Martin, executive director of the Consortium of Universities for Global Health in Washington, D.C. "It's going to enable countries around the world, particularly low-income countries, to be able to produce these vaccines and distribute them in a way that's going to affordable, effective and safe."

The story of CORBEVAX begins some two decades ago. Peter Hotez and Maria Elena Bottazzi were medical researchers at George Washington University in Washington, D.C., where they worked on vaccines and treatments for what are called neglected tropical diseases, such as schistosomiasis and hookworm.

When a strain of coronavirus known as SARS broke out in 2003, they decided to tackle that disease. After moving to Houston to affiliate with Baylor College of Medicine and the Texas Children's Center for Vaccine Development, they created a vaccine candidate using protein subunit technology. This involves using proteins from a virus or bacterium that can induce an immune response but not cause disease.

"It's the same technology as the hepatitis B vaccine that's been around for decades," Hotez says.
The goal: at least 40% vaxxed in all nations by year-end. This map shows how we stand
Goats and Soda
The goal: at least 40% vaxxed in all nations by year-end. This map shows how we stand

Their SARS vaccine candidate looked promising, but then the SARS outbreak petered out. No evidence of disease, no need for a vaccine.

When a new strain of coronavirus triggered the COVID-19 pandemic, Hotez and Bottazzi figured they could dust off their old technology and modify it for use against COVID-19. After all, the virus causing COVID-19 and the virus causing SARS are quite similar.

Hotez says they tried to interest government officials in the vaccine, but they weren't impressed.

"People were so fixated on innovation that nobody thought, 'Hey, maybe we could use a low-cost, durable, easy-breezy vaccine that can vaccinate the whole world,' " Hotez says.

"We really honestly couldn't get any traction in the U.S., but our mission is always to enable technologies for low- and middle-income countries production and use," Bottazzi recalls.

So they turned to private philanthropies. A major donor early on was the JPB Foundation in New York.

"The rest were all Texas philanthropies: the Kleberg Foundation, the [John S.] Dunn Foundation, Tito's Vodka," Hotez says. The MD Anderson Foundation also chipped in.

"When people say, 'Why did we move [from Washington, D.C.] to Texas?' Well, we knew that this was a great philanthropic environment. So this is really very much a Texas vaccine," although there were other, smaller donors from all over the country.

Hotez says that unlike the mRNA vaccines from Pfizer and Moderna, and the viral vector vaccine from Johnson & Johnson, protein subunit vaccines like CORBEVAX have a track record. So he and Bottazzi were relatively certain CORBEVAX would be safe and effective.

"And it's cheap, a dollar, dollar fifty a dose," Hotez says. "You're not going to get less expensive than that."

Clinical trials showed they were right to be confident CORBEVAX would work. An unpublished study conducted in India involving 3,000 volunteers found the vaccine to be 90% effective in preventing disease cause by the original COVID-19 virus strain and 80% against the delta variant. It's still being tested against omicron.

But CORBEVAX is already entering the real world. Last month, the vaccine received emergency use authorization from regulators in India. An Indian vaccine manufacturer called Biological E Ltd is now making the vaccine. The company says it is producing 100 million doses per month and has already sold 300 million doses to the Indian government.

"The real beauty of the CORBEVAX vaccine that Drs. Hotez and Bottazzi created is that intellectual property of this vaccine will be available to everybody," Keith Martin says. "So you can get manufacturers in Senegal, and South Africa and Latin America to be able to produce this particular vaccine."

By contrast, the makers of Pfizer and Moderna, for example, are not sharing their recipe.

One drawback to the CORBEVAX technology is that it can't be modified as quickly as mRNA vaccines can to adjust to new variants.

That forces public health officials to make difficult choices.

"Something which can be adapted the fastest versus something that can be adapted relatively quickly, but then more importantly can be manufactured at a large global capacity and at a cost of production which is much lower," says Prashant Yadav, senior fellow at at the Center for Global Development in Washington, D.C. The thought is some protection may better than no protection.

Of course, the ideal vaccine would have both qualities, and Hotez is at work trying to develop technologies that can do that.

"There's no issue with pushing innovation," he says. "I think that's one of the really positive features of the U.S. vaccination program for COVID. The problem was it wasn't balanced with a portfolio or oldies but goodies."

Hotez is hoping his oldie but goodie will usher in a brighter future for the world.

Might be hard to wean some off the graphene oxide though.

Hmmm, Imagine that.......

We'll know how effective it is by how much they attack it and anyone that mentions it.

Plus, there are no patent rights on it from what I read. It costs $1.50 a shot to produce. How's big pharma going to react to that ?

kwg

No matter. By the time they pay for FDA “emergency approval”, it’ll be $250 per dose.

won t work, its not a part of the narrative in their war gaming.

They say mRNA vaccines are easy to change with regards to new variants, yet they are still pushing the original cocktail that doesn't work against the new variants. And their solution is to now mandate 4 jabs of the original ineffective recipe.

Saying it’s harder to change against new variants is no big deal. This one keeps you from getting covid. The others do not. Changing the others will still not keep you from getting covid. Old school might win. Edk

I'd certainly take this shot before any of the others. This may be 'old school', but from what I understood, it works way better than any of the others.

I thought India had no worries because they were taking the highly dangerous, experimental, off label drugs like Ivermectin?

Sounds like just another angle for the globalists to get their poison in an unreached demographic to me.

You mean white blood cells?

When Twitter bans mention of this actual vaccine, we’ll know it’s a good thing.

Mp

They already did.

Oh, its effective. Its doing what the cabal wants it to do.

Saw this mentioned the other day, reporter asked Fauci about it

He got all uppity and total assy about it.

That might be telling in itself

India still has no worries.

The schit that may be harmful and doesn't work is intended specifically for first world, largely white populations.
India will use it, it will work (like real vaccines do) and it will never see the light of day in Oz, the US, Germany, etc..

Japan is working on one too, one shot, lifetime protection.

https://www.japantimes.co.jp/news/2021/12/29/national/science-health/one-shot-lifetime-covid-vaccine

That's exactly right.

No chance that this flies here with the corruption involved.

How does it differ from the other adenovector vaccines,...such as the J&J and Astra-Zeneca?