I have been messing with the 450 Bushmaster for 3 years now with different loads and bullets. My go-to pet load is 44 grains of H110 in 450 BM Starline brass, CCI primers, Bear Creek Ballistics 240 grain HV bullets, and a 2.6" COL. Feeds great in 2 rebarreled Mausers and 2 Savage 99's rebarreled to 450 BM, one in 16", the other in 20". Consistent 1 ragged hole groups between rifles. Tested on 3 deer this season, all dead right there out to 200 yards. This is a viable option. Around 2,500 FPS and 3400 ft lbs.
My prior go-to was 38 grains of lil-gun, book COL, and the HDY 250 FTX same accuracy but the bullets can come apart and sometimes not exit.