At least 2 popular DT angles. Brownell's sells cutters for both, maybe more. Requires a milling machine. Doubt a drill press with a milling vest would do. You're correct, some barrels are pretty hard & put up a pretty good fight with a hand tool, depends.
Your DT slot will only need to be as deep as the thickness or male DT of the base of the sight. Most any rifle barrel will have enough wall thickness. But check anyway.