Well, I tested some of the common bullets this past weekend to see if I could see any objective differences. Unfortunately I only had time and materials to do one test of each sample a single time so the sample size is suspect. Here is what I found:
Left to right the bullets are Hornady XTP (standard, Colt), Speer, Sierra, Hornady XTP (magnum, Casull), 325 grain cast. All the jacketed bullets started at 300 grains.
The penetrations in the common test media (wet newspaper) were (respectively): 12", 19.5", 24", 24", 25" at a distance of 27 yards.
I was firing the loads from a carbine but I wanted to compare penetration at revolver velocities so I guessed at some lesser loads (10.5 gr. 800-X) which gave me 1121 fps averages, just a bit lower than I wanted.
Since expansion was minimal at most for all but the standard XTP I would have thought the penetration would have been similar. The difference between the Speer and the others seems to beg for additional tests. I do know from previous experience comparing the various bullets informally in failure media that the Speer is softer than the Sierra.
A footnote:
I also tested the Speer 350 FN (45-70) in the same media at the same distance. I was firing these bullets in a load that generated over 1900 fps. This is how they ended up:
They accomplished 16-17" penetration.