Meant to say IMR-7828 shows signs of pressure!!! I predominantly shoot 150 to 160 gr. bullets in my 280. Leave the 140's for my 7mm-08. With 160 grainer im able to achieve 2950 fps with imr-4831 and almost 3000 fps with 7828 (28" barrel of course)
I don't have a 280 but RL22 and 160gr Partitions are a sweet combination in my 7x64 so there's a real good chance the same pairing would be handy in a 280.