I have one of the early 629 "Classics" with full lug barrel. Don't recall if it is a 629-2 or 629-3, but S&W confirmed for me it has the endurance package.
If we're talking heavy non-expanding bullets, WFN, LFN, or whatever, 1200 to 1300 fps may give your best penetration anyway, and super-hot loads don't buy much.
I would not shoot any hot loads in a .45 ACP, or .45 Colt N frame. The .41 mag, or .357 Mag in the N frame, that's a different story. Or shooting expanding bullets, then I want the things to expand as much as feasible, while still having sufficient penetration.