Between my late wife and I we shot over 200 antelope.. Saw or used everything on them from the .22lr through the .375 H & H and the .45-70.. Also killed a bunch with the .44 mag. pistol.. Our favorites started with the .270 on up.. Killed quite a few with the .25-06, but have come to like the .270 better.. My wife's favoite was a custom .7mm Rem. Mag.. I used or still use a variety.. This year a .44 mag., a .300 Sav., and her old 7mm mag..
Saying hitting them where they live is not considering the distances, and here the wind.. I can hit one where it lives with a .22 LR, but it might not die for a while..
The best shot I ever saw made was buy a good friend.. It was a dandy buck, about 400 yards in a very heavy wind.. He put a 165 grain Speer BT though the lungs. Using the hood of the truck for a rest.. Fired from his .300, the bullet dropped about 10 inches, but the drift was more than a foot.. Something to consider..
