Start with a 22rf. Then get a 357 magnum. Then get a 44, 45 or something bigger if you find the need.

If you start with too powerful of a handgun at first you'll develop a flinch and it will be very hard to get rid of. I made the mistake of starting out with a 44 mag even with a fair bit of handgun experience, and am still fighting the flinch I developed 20 years ago.