Sierra GameKings are what I've used the most, never had a bad experience but deer are easy targets for the most part.
They normally are very accurate which leads to confidence in taking shots, performance on game has always been stellar. If I want a tougher bullet the partition is my choice.
Good post Matt. I know a lot of guys turn their noses up to the GK, but they do work and they are accurate. As are the Hornady btsp and sp interlocks. Deer are NOT hard to kill, any old damn bullet is going to work. An accurate one is one I'd be looking for. Hell even the Winchester powerpoint is a great deer bullet and is damn accurate in my rifles: