I have tried the 145 LRX and 139 LRX. My barrel much prefers the 139 grain. And, it's not a twist rate issue. Granted, I didn't test variables in each load, so it could have been improved with some experimenting.

For RL22, I use a long drop tube on the powder funnel. Pour slowly and the powder will fill nicely on it's own. A few light taps will also help. I run 70.0 under a 110 TTSX for 3597 fps