I've not used it to date in a 308 on game but have taken a plethora of game with it in the .06 and the 300's.
Personally I feel it is the toughest bullet that Sierra makes and is every bit as good if not tougher than all the other non preme's out there.
It's an accuracy favorite of mine for my LVSF 308, but the only thing I've shot with it was a small pig. I wasn't really worried, but having read your comment I'll have no qualms about busting a big buck with one. Where I'll be hunting 300 yards is a long shot, so even launched around 2650 fps I'm sure the spud will do all right.
mathman
Oops, I forgot we were in the Elk section.
