If I had to choose one from my collection, it would be my customized .280 Remington shooting 140 accubonds through it's bombproof B&L 3-9x40. I trust it completely, and with todays amazing bullets, it could easily be the ultimate for me.
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I'm with the
depopulator, except I'm partial to the 2.5x8 Leupold.
Love the .280. Love the accubombs.
sk