In 6mm, 6.5, and 7mm, I like having bullet options, paper, varmints, deer, etc.
On mid bore, I found w/338/06 I used 2. 200 BT for deer, and 225 PT on elk.
For a 350RM, I used 2 for hunting. 225 Sierra deer, 225 PT on elk.
Plinking sometimes done w/cheaper 158s and 200 CLs.
My Point is, bullet selection is nice, but when I am using a mid bore, the rifle is predominantly loaded for big stuff. ONE good bullet will do the job. Well, if you place it
Choice? I like both, flip a coin and ENJOY, it's small potatoes IMHO.
