225 vs 210 yields a very small diff in trajectory, more energy and SD/BC. Now a 250 is great, but out yonder it falls faster, how far do you need to shoot.

For me, a good 225 PT/TSX, or 230 FS is a great all around bullet.

Steelhead has it right. You can only shoot one rifle, and if you have ONE good bullet, it WILL handle all duties from Deer to Grizzly IMHO. Choices are fine, a 200 BT/NAB will shoot flat at 2900, more than the 225 at 2670, but I'd keep the light stuff for deer in this round and prefer the extra payload of a 225 on big stuff, 250s would be find up to say 300 yds or so, as would a well loaded 350 RM or Whelen.

Not played with a 9.3 yet so no opinion on 'go to' wt. but I could be happy with either round on a big game hunt. I believe the 338 I feel has a tad more reach, if one truly needs it.

They ALL will kill just fine when steered properly.

A CZ 9.3 might be a solid choice given economics if money is tight as most 338/06 are custom. A rebored Sako pre-G '06 might be an option to consider.