Depends on the "mate" cartridge you have for it?
If you have a .338 then the .416 is the common mate. If you have a .300 then the .458 is the common mate.
I have owned both and prefer the .458. It hits harder, has more caliber, more bullet weight for dangerous game, and still has a slew of quality light weight bullets that replicate .416 recoil levels, velocities and trajectories where .40 caliber rifles are used.
JW