OK, so if I am reading this correctly....I am finishing a custom build chambered for the original .280 A.I.. I had been planning on using the Nosler 140 gr. ammunition, but now am thinking this is not a good idea? I am confused on whether the answer is Yes, No or Maybe...

New to customs, so any help would be greatly appreciated...

I have put waaaay to much into this rifle to risk catastrophic failure.....