A stainless 308 or 30-06 with a 2.5-8X Leupold would be my pick.
Here's mine from this morning... Kimber 308 Win and 2.5-8 Leupold:
"after the bullet leaves the barrel it doesn't care what headstamp was on the case" "The 221 Fireball is what the Hornet could have been had it stayed in school"