Both can find ammo readily, and there are plenty of places online that you can order it. It will come down to which platform you prefer if you want a semi automatic then by all means the 10mm is for you, if you like the wheel gun than a 41 mag is in line. Smith and Wesson does make a 10mm in a wheel gun as well. Either one is capable of taking medium game. There use to be a company called DoubleTap, I believe they are still around and make plenty of 10mm ammo.

Last edited by Esox357; 09/07/11.