Folks tend to aim a little low on a frontal, myself included.
I started shooting maybe six-inches higher and it picks up the spine every single time. That dumps them most rickey-tick.
Steve
+1 Aim for the throat patch.
Yup doesn't matter the projectile; bang-flop.
Amen on that shot placement. Not only does it take out the spine, but blows bone into the heart, lung, liver region.