What do you mean by "bigger game?"
I've got both. Years ago I was looking for a 444 when I found a .45-70 and bought that. Last year I finally got a 444, but haven't taken any game with it yet. My .45-70 has a straight grip and hard plastic cresent but plate, and the 444 has a pistol grip and recoil pad.
The difference in recoil between the two is significant. By that I mean I can shoot the 444 better, and good enough for a higher number of rounds. There isn't much difference in the cost of reloading. Of the two I like my 444 better.