Vapo-I absolutely love the 160 Noz out of a .270. I generally run R22 and accuracy is fantastic, speed very good (2800ish) and it will penetrate like a 200 out of a 300 mag. As for the twist comments I've not seen a 10 twist .270 that wouldn't shoot really well with it.
Very tough to beat and way underrated, oddly enough generally by those who've not used it...hard to believe but true...
Dober