I lost a pig three months ago. Shot at 150 yards found blood and bone. Guide watched him and didn't think it was a leg shot. Tracked him for two hours and lost him. Found blood and then it would dry up, found where the pig laid down and then got up and where it pooped but no pig? Hit with a handloaded 168 TSX from a 30.06. I was not happy about it. The pig was probably 130lbs. I nailed a big boar with a 25.06 115 bt and he dropped at the shot only to get up and try to make it to the wood line and I put another in him he was anchored, walked up to him to have him jump up with his head snapping his jaw and popped a 40 caliber gold dot into him, dead right there! The hogs can be tough. I have not lost a deer yet, but sure it is possible. Hunt long enough you will miss and you will lose game? It sucks but it happens as a hunter, ethically do all you can do to recover the animal!