I would choose the super grade in 300WM.

The super grade part of the equation is a no brainer so let me explain why 300WM. I've spent years buying most of the popular calibers and then some but one I've never owned is the 300WM and if I were to be honest with myself and the hunting I do, I have concluded at least for me, that it's the best one gun caliber. The answer for you might be entirely different but you have to give the 300 at least an A for versatility. Good luck on whatever you pick.