We shot a medium size doe last weekend. She took about two steps, twirled and dropped. Used 55gr TSX VorTx ammo and a 20" AR15. We have been using a .280 Rem and a 30-06 in the past. I'm very impressed with the damage (boiler room) and she did spray blood, enough to follow if needed. I'm not looking at going with the 55gr or possibly 62gr in my 223 as well. Not sure why we use a larger gun smile