I have a friend who has a Leup red dot on a S&W 625, and a Trijicon red dot on a FN 45 auto. I've played with both and find myself searching for the dot in the light. It takes me alot longer to line up/find the dot than regular irons. It could be I don't have enough rounds down range for it to work for me.

10mm Glock is never a bad choice, as long as your not firing thermo nuclear rounds. Gunbroker has a dealer in Ohio that's taking Lone Wolf slides and putting them on Glock frames. You get a choice in barrel length, and a ported barrel or compensator should you want one. About 800.00ish if I recall correctly.

Or you can get one of five Sig 220's that should be out by May. All of the semi auto's on the market have more rounds on tap than a revolver.