I tend to like the 10mm as an auto pistol round myself. On the other hand, I can easily see why you'd like a lighter 10mm revolver.
Since you've had both the 10mm and the .41 Mag in revolvers, I need not point out the differences to you.
In auto pistols, no way would I ever consider a Glock, especially for hunting. Their "stapler" trigger break would be enough. Their inability to handle high pressure loads is another. It's easy to overload a 10mm with handloads.
I see no reason why you shouldn't do the custom revolver. But, if you go with an auto pistol, I'd recommend a stronger gun with a much better trigger break. E