I have tried H4350 in my 260 from 123 to 140 gr. My barrel does not care for it. I tried lots of loads and ES /SD numbers were awful, and it showed down range. I have a big jug of H4350 sitting on my shelf and no current use for it. However, H4831 works awesome with 140's. Varget / IMR 4064 works great with 123- 130's. All powders provide single digit ES. My current load is 40.1grs Varget with 130 VLD Hunting, shoots bugholes at 100 yards and 1 1/4" groups at 400 yards with less than 1" vertical.