For whatever reason, the best powders in the 22-250 were not the best powders in the Swift, even with the same bullets. I mostly use TAC in my 22-250 with the 50s. I liked H380 when I shot 55s.
I agree with this, H380 and 55's always worked well in my 22-250's. In my swifts H380 is my least favorite powder.
Powders like one of the 4895's and Varget worked well in my 22-250's but never worked in my swift's.
The only powders I have found that work well in both is 4064 and RL15, as I mentioned earlier my favorite swift powder is W760/H414 and I seldom use it in my 22-250's
