I have a .280AI that shoots 160gr Sierra's into very small groups, but it shoots the 160gr NPT just as well. I too have found that NPT seems to shoot better at max. pressure. Also, I have seen that a small run out factor affects the Nosler bullet more than the Sierra. I do not have a clue why that might be. I like accurate rifle/load combo more than I should because in the field(speaking for me only)what the heck does it really matter if the best my rifle will do is 1.5" or so. I'm not shooting at an unwounded deer or elk past 450yds or so anyway.