My 30.06 prefers 180 grain bullets. Nosler tends to be very picky with seating depth to get them to shoot accurately in my experience. I find .20-.30 off the lands works best in my rifle for seating depth. I am using 58.5 grains of Reloder 22 for 180 grain projectiles which is working great. I'm not sure the velocity that I'm getting from them but the accuracy is there!