I have shot only 1 deer in my life from prone, and one elk seated using a tripod and special head {the Gun Claw}. One elk offhand and one lion offhand (that with a bow). Dozens using a rest, such as a treestand or tree, or truck tailgate, and a few seated. Never shot anything offhand more than 32 yards away (bow).
It's normally too thick for prone shooting where I end up, but of course it's great when you can.
