75 V-max with around 48 grains of Varget, RL15, or IMR 4064, or a heavier load of IMR4350 / H4350 have all shot well in a number of different brand 25-06 for me.
RL19 or RL22, IMR 4350, either 4831s or Retumbo have been accurate in 100 grain loads. I have shot tight groups with all these.
Been putting IMR 4064 under the 75s (Marlin), H4831 under 90 HPBT (Tikka) and RL19 under the 100 NBTs (Sendero) this year.
Only shot one yote with 85 NBT last year (don't remember the powder) but the size of the wound and the way it was smoking I thought I caught it on fire!
If you have an accurate / fast 100 grain load I would stick with it for multiple game. It puts coyotes down hard and fast and doesn't do quite as much damage.
