The 50's seem to make the most sense if you want to sling a 400gr bullet. But the logistics make me lean toward a .475 right now.
Buffalo Bore is the only place that seems to have JRH brass and it's expensive as fugk.
Travis
I am going with a 480 Bisley. I shot a friends and honestly its no more of a handfull than a hot loaded 45 colt or a 44 mag.