I used 47/Varget under 120s, 3050-3100 in 21" OEM 700s. Partial sized RP brass......as always, when I post a load, it was safe in MY firearm.

On that 280, my first rifle was a 7RM, I ran Speer 115s at 3375. You'd thought you were shooting a 220 Swift, but the recoil was not light after a dozen or so rounds.

I'd personally want to run at least a 140 and likely a 150 in a 280 class round, to make use of the BC. A light mono if accuracy might also be chosen if not shooting LR.