Learn to read pressure signs and put the chronograph away till you have the load you want. Then chronograph the load. Be terrible if the chronograph just happened to give the wrong reading now and then and you blew up your rifle!
I use my chronograph through the whole process from the starting load to the max load. I shoot through the chrony every time I change the weight of the charge. To me speed is one of the pressure signs. I usually get to where I want that way without any other pressure signs. I once got max velocity with the starting load.