I would never ever shoot any lubed cast bullets in a Hybrid....

Loading for sub-sonic rule of thumb is minimum 60% of available case volume with bullet seated as close to 100% powder burn in your barrel length. A accumulation of too much unburnt powder in your suppressor can cause a secondary detonation.

I've done a lot of sub-sonic work with the 450 Bushmaster and 45-70....best powder is Trail Boss 100% burn in a couple inches of barrel. Load densities start at 70% you can load up to 100% and do not compress powder.

Some great bullets available for sub-sonic....Makers Bullets....https://makerbullets.com/products.php?cat=3&scri=64
Outlaw Bullets...http://www.outlawstatebullets.com/4.html
Remington 405 gr. cup-core

In your 45-70 a Remington 405 gr. cup-core with 13 gr. of Trail Boss is sub-sonic at 1010 fps in a 16" barrel at 70 F 785' elevation 30% humidity, .5 gr. more depending on conditions may be above sub-sonic. Its very quit had a guy at the range ask me what kind of air rifle it was....lol... Ruger #1