S2s can be finicky. I've had great luck with various 150s in many 300WMs with H4895, IMR4350, and IMR4007SC, but many other powders will work just fine.
They're known more for great termial performace, not necessarily for great accuracy.
But, I've found if you treat them like a VLD, work with the jump, sometimes they'll surprise you.
They like to jump. I have on occasion, increased the jump until they shot pretty well.
Give them a chance. Once you have the right combo, you gotta good round.
DF
