Was in the Toyota dealership the other day kicking tires. They had an article of a guy with a 2008 Tacoma that had reached 1.2 million miles with the same tranny. The engine was replaced at 880K. The guy delivered nuclear medicine and used the vehicle as his transportation.

I have a 2006 Duramax with 132,000 miles. Years ago, I had a Toyota P/U with the 22RE engine. I don't think you could kill that engine.